does glp-1 really work to lose weight DYK GLP-1s are now approved as a daily pill for loss 💊 No injections required. These medications can also help regulate blood sugar—but they're not one-size-fits-all. Talk with your doctor about GLP-1 Weight-loss Motivation : r/Zepbound

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Japan approved semaglutide 2.4mg for obesity in 2023

GLP-1 (Semaglutide): Reduces appetite Slows gastric emptying Increases satiety Supports sustainable calorie reduction Average weight loss: Up to 15% in 68 weeks (NEJM 2021) GLP-1 + GIP (Tirzepatide): GLP-1 + GIP synergy boosts insulin sensitivity Enhances metabolic balance Further suppresses appetite and cravings Average weight loss: Up to 21% in 72 weeks (SURMOUNT-1) Compounded vs

These integrated actions position incretin-based therapies as uniquely suited to address the complex, multifactorial pathophysiology of MASLD [19]