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In addition, fGSH/GSSG was significantly higher in participants receiving co-enzyme Q10 (mean (s.e.), no co-enzyme Q10: 8.2 (0.4), co-enzyme Q10: 9.8 (0.4)

Antioxidants are adjunctive to medical therapy Oral antioxidants include vitamin B, C, polypodium, glutathione & melatonin Topical antioxidants include vitamin B, C, E, & ferulic acid Oral antioxidants are easier to use for most patients Topical antioxidants can be considered in some patients Skin irritation is the most common side effect of topical antioxidants, esp