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GHK-Cus clinical skin improvement studies were conducted primarily in women, making the skin regeneration research particularly directly applicable

It was initially planned to recruit 20 analyzable patients (who completed the two-treatment periods) to have 80% power to detect, with a two-sided test at 0.05 significance level, an absolute decrease in percentage over total target of 10% under the A-dopamine period compared with the control (oral l-dopa-alone treatment) period, by assuming a standard deviation of 15% and a within-patient correlation of 0.5 to account for the crossover design

Different combinations of the proteins encoded by these two genes generate tissue-specific isoforms of the functional enzymes