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Europe, building on FP6, provides market analyses and exploitation tools to support consumer demand expansion (European Commission, 2009

(2) discovery of novel diagnostic/therapeutic biomarkers

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The brainstem-cortex network plays a critical role in the migraine pathway, with conditions such as insomnia, obstructive sleep apnea, sleep-related movement disorders, and REM sleep disturbances closely associated with migraine onset ( 3.2 Pathophysiological mechanisms of migraine The pathophysiological mechanisms of migraine are complex, and multiple hypotheses exist