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It was first isolated from human plasma albumin in 1973 by Dr

(10) Kuznik BI , Pateiuk AV , Baranchugova LM , and Rusaeva NS (2008) (Effects of epithalon and cortagene on immunity and hemostasis in neonatally hypophysectomized chicken and old birds)

Brain Sciences (2021) This study by an independent research group (outside the original Washington State University team) demonstrated that Dihexa rescues cognitive impairment in an Alzheimer's disease mouse model (APP/PS1 transgenic mice)

And some of these studies in rats involved a complete transection, not just a partial tear, but a complete cut of a given ligament or tendon or nerve pathway