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In 2011, a study revealed that the administration of phenformin in combination with 2-deoxyglucose can prevent the development of lactic acidosis, reducing toxicity

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In response to 16 days of supplementation with 3.4 g/d, L-citrulline significantly increased plasma citrulline, arginine, and nitrite levels, and also increased muscle oxygenation

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10.1042/CBI20110566 Cell Biol

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ANTIOXIDANT DEFENSE SYSTEM GLUTATHIONE REDOX COUPLING AND NITRIC OXIDE SIGNALING Free radicals are unstable atoms or molecules with odd (unpaired) electron(s) that can start a toxic chain reaction on important cellular components such as DNA, or the cell membrane

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