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found that elevated GSH in the TME cooperates with immunosuppressive IgG4 antibodies to weaken antibody-dependent cellular cytotoxicity and other effector functions, driving macrophages and lymphocytes toward a tolerogenic state and thereby significantly promoting tumor immune evasion and growth (76)
154,155,156,157 Currently, the CRISPR/Cas9 system can enter cells for gene editing in three forms: the Cas9: sgRNA ribonucleoprotein complex, mRNA for Cas9 translation alongside a separate sgRNA, and a DNA plasmid that encodes both the Cas9 protein and sgRNA
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What about effects on inflammation and oxidation
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