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The simplest way to think about them is in two buckets: stomach symptoms during dose escalation, and a separate skin-sensation signal at the highest dose in Phase 3
doi: 10.1172/JCI.INSIGHT.156549 224 Amylyx Pharmaceuticals Announces Interim Data From Ongoing Phase 2 HELIOS Clinical Trial Demonstrating Improvements in Pancreatic Function and Glycemic Control with AMX0035 in People with Wolfram Syndrome | Amylyx
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