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This effect is highly similar to the ScGrx7 mutants K105A and K105Y (Figs 2 and 3)
The most common side effects are gastrointestinal, including nausea (occurring in 20-30% of patients), diarrhea, vomiting, constipation, and abdominal discomfort
Adding water after initial reconstitution is acceptable as long as you maintain sterile technique and account for the new total volume in your calculations
The gut microbiota and irritable bowel syndrome: friend or foe
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