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It plays a role in how cells move and respond to injury
Conversely, patients who respond well may continue treatment indefinitely as part of comprehensive weight management, similar to the approach used for other chronic conditions such as hypertension or diabetes
The role of GLP-1Rs on tanycytes remains to be fully characterized, but they may be involved in transport of semaglutide into the ARH
Regarding thyroid effects: preclinical studies in rodents have identified C-cell changes with GLP-1 receptor agonists, though the relevance of these findings to humans has not been established
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