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Anyone taking methyl-donor-sensitive medications (some psychiatric drugs, methotrexate, methylated B-vitamin protocols at high doses): NNMT shares the methyl donor SAM, so theoretical interactions exist
Rhabdomyolysismuscle breakdown severe enough to cause kidney damageis extraordinarily rare with tirzepatide and has not been documented in clinical trials
And that's where that phenotypic work comes in handy
Large meals or high-fat foods challenging to digest when your stomachs functionality is already slow
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