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The tirzepatide peptide itself can contribute a very faint yellowish tint at higher concentrations, though this is usually overwhelmed by the pink from B12 when both are present
As the American Society of Health-System Pharmacists puts it in its guide to assigning beyond-use dates: "Ultimately the assigned BUD should default to the more conservative dating after an assessment of sterility and stability." Stability is the peptide chemistry
Unless someone is getting B6 over 25mg a day for quite a long time, its highly unlikely for adverse effects to be seen
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