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[86] found that semaglutide, as a GLP-1 analog, can directly act on fat cells, increase the expression of thermogenic genes for browning phenotype maintenance, improve the expression of UCP1, mitochondrial biosynthesis and thermogenic marker, thereby contributing to weight loss
Off-label use and lack of clinical evidence The primary concern with microdosing GLP-1 RAs is the lack of scientific evidence
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It works depending on consistency and lifestyle, as well as skin type
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