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Mechanistically, NCOA4-mediated ferritin autophagy plays a crucial role in maintaining intracellular iron homeostasis by promoting ferritin transport and iron release[113]
Oxidative stress in polycystic ovary syndrome
As Nrf2 germline knockout (KO) mice were used in those early studies, it remains unclear whether the minor muscle regeneration defects seen in Nrf2 -KO mice was due to defective MuSCs or defective niches
In addition, GLP1-RAs demonstrate numerous cardiovascular protective effects in subjects with or without diabetes
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