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Find out if the dietary supplement Relief Factor is likely to help relieve aches and pains, if it is safe, and if it is worth the cost
A total of 40 participants were selected and randomized into two sequences in a double-blind, placebo-controlled crossover design, with a one-week washout period between treatments to eliminate carryover effects
Mannitol, with a cross-sectional hydrated diameter of 6.5 is a small solute that is used as a marker of total intestinal surface area available for absorption, whereas lactulose (with a larger cross-sectional diameter of 9.5 ) is used to assess the paracellular permeability through the tight junctions normalized to the total available intestinal surface [32], with results expressed as a ratio of the permeability of mannitol to lactulose
Kreymann B, Ghatei MA, Williams G, Bloom SR
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