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*Correspondence: Predrag Sikiric, [email protected] This article was submitted to Gastrointestinal and Hepatic Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

BPC-157 may help by: Supporting blood vessel formation (angiogenesis) to deliver oxygen and nutrients to healing tissue Supporting collagen production and connective tissue repair Helping regulate inflammatory signaling (so the body can shift from inflamed to healing) Supporting gut lining integrity and GI repair pathways TB-500 may help by: Supporting cell migration and tissue remodeling (important for recovery and regeneration) Supporting muscle recovery and range of motion Helping reduce stiffness and supporting mobility in overworked areas Supporting recovery when injuries involve multiple tissue layers (muscle + fascia + connective tissue) In simpler terms: BPC-157 focuses heavily on targeted tissue healing and inflammation control , while TB-500 is often used for broader recovery, mobility, and tissue regeneration support