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First, the histidine residue in the sequence creates a stable binding site for the Cu ion this is a classic copper-chelating motif that makes GHK a physiological carrier of this element
Lancet 392 (10157), 15191529
Use your GHK-Cu one night and your retinoid or acid the next
GHK-Cu is widely used in cosmetics and considered well tolerated topically, but it is not a medical treatment
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