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This, in turn, has been demonstrated to result in the up-regulation of PD-L1 expression, the reduction of CD4 and CD8 T-cell activation and tumor infiltration, and the promotion of the growth of pancreatic ductal adenocarcinoma (PDAC) cells [112]

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Indeed, China, the USA, and Brazil published many articles on AFG1 and ranked first to third countries to conduct research in this area