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In terms of adverse drug reactions, aggregated data from phase II and III studies indicate that while dotinurad can potentially cause liver-related adverse reactions, such as hepatic steatosis and abnormal liver function tests, which the incidence is lower compared to benzbromarone
If you have been off for more than 4 weeks, the labeled approach is to re-titrate starting at 2.5 mg weekly for 4 weeks, then stepping up in 4-week intervals
Are all GLP-1 injections the same
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