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Purging resolves on its own within 4 to 6 weeks

[119] fabricated a bilateral microneedle patch to deliver cyclodextrin-based metalorganic framework (CD-MOF)-encapsulated DXMS and paeonol to overcome the disadvantages of conventional intranasal administration, which not only enhanced the therapeutic effect of the drug but also reduced mast cell degranulation and modulated Th17/Treg cell homeostasis

These findings support the continued use of GLP-1 RAs in clinical practice, but further research is needed to fully understand their long-term oncological safety, particularly in relation to non-gastrointestinal cancers and rare malignancies such as pancreatic cancer