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For full-length COP1 , it was constructed as a N-terminal Glutathione S-Transferase (GST) tag followed by a TEV cutting site
& Mukhopadhyay, K
Some cosmetic-science programs also incorporate this formulation into ingredient-comparison studies, evaluating it alongside retinoid analogs or other peptide actives on reconstructed skin models
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It highlights intercellular lactate shuttling, intracellular lactyl-CoA-driven protein lactylation, and the lactate-GPR81-TAZ-PD-L1 signaling axis that facilitates immunosuppression
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