They are now part of a broader medical discussion about obesity, insulin resistance, cardiovascular risk, fatty liver disease, inflammation, body composition, appetite signaling, and long-term metabolic health
Winlevi (clascoterone, Sun Pharma), approved in August 2020 for hormonal acne, is a good option, Tolkachjov said, as it targets specifically the hormonal type of acne that we think is going on here due to the weight changes. As dermatologists treat GLP-1 receptor agonist-induced acne, Tolkachjov encourages practitioners to communicate this possible side effect to their patients moving forward
Patients who are actively trying to conceive or planning pregnancy within the next few months should discuss whether initiating semaglutide is appropriate, given the FDA recommendation to discontinue the medication at least 2 months before planned conception
Many people also notice a stronger drop in appetite at first