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2mg is the Phase 2 starting dose and produces clinically meaningful appetite suppression for most users
Unfortunately, most Glutathione supplements have nearly no bioavailability, as the molecule breaks down rapidly after oral ingestion
For instance, in the pivotal SURPASS-2 trial, patients receiving the highest tirzepatide dose (15 mg) achieved a mean body weight reduction of 11.2 kg, nearly twice that observed with semaglutide 1 mg (5.7 kg) (19)
The secondary outcomes included individual electrophysiology measures, vibration perception, clinical neuropathy changes, etc
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