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4% (placebo) due to adverse events Clinical Significance: This pivotal Phase 2 study established cagrilintide as an effective monotherapy for obesity, producing weight loss competitive with GLP-1 agonists but through a distinct mechanism
Additional comfort measures: Apply a cold compress to the injection site for 3060 seconds before injection to numb the area slightly Relax the injection areatense muscles can increase discomfort Distract yourself during injection (conversation, music, or focused breathing) Avoid injecting immediately after exercise when blood flow is increased After injection , do not rub the site vigorously, as this may affect medication absorption
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