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The effects of tirzepatide on lowering systolic blood pressure and increasing heart rate may contribute to its beneficial effects in patients with heart failure with preserved ejection fraction. The researchers said gastrointestinal symptoms affected 6.3% of participants in the tirzepatide group and in 1.4% of those in the placebo group
Does semaglutide fatigue go away
The reduction in NT-proBNP when viewed alongside the lower number of HF events in the semaglutide group in the STEP-HFpEF program (albeit with small numbers of events) signals that semaglutide has beneficial HF effects
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