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Even if, in the first couple years of Mounjaro and Wegovy both being approved for the weight loss indication, the impact from just those taking it who can afford it/have the insurance for it can be significant
Indeed, evidence indicates that VMAT2 is the only monoaminergic neurotransmitter expressed in CNS neurons
Serum metabolome analysis disclosed reduced GABA levels one year before seroconversion to insulin autoantibodies (IAA), but not before the appearance of GAD antibodies (120)
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