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Understanding these effects helps patients and clinicians manage them proactively rather than discontinuing treatment prematurely
Ethical Statement This article is a narrative review of previously published studies and does not involve new data collection involving human or animal subjects
All TPP-dependent enzymes contain a highly similar TPP-binding domain and its lack in the TKTL1 encoded protein strongly suggests that it is unlikely that TKTL1 is a TPP-dependent protein capable of catalyzing the transketolase reaction
doi: 10.1007/s12035-017-0544-0 129 LiuL
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