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This becomes relevant for diabetes because blocking the SGLT2, and therefore preventing that reabsorption, allows excess glucose to be excreted in the urine rather than returned to the bloodstream
Sigman, M., Glass, S., Campagnone, J., and Pryor, J
However, AMPK activity in the LH was still low, and exendin-4 treatment decreased AMPK activity in the VMH, whereas no significant effect was detected in the LH (Figure 5)
(4)(5) The difference in their mode of action is the pathway by which they exert their action
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