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But once you add water back, freezing creates ice crystals that can physically disrupt the peptide molecules
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This pattern aligns with B12 pharmacokinetics: serum levels peak 8-12 hours post-injection, tissue saturation occurs over 48-72 hours (Andrs et al., Journal of Blood Medicine , 2018)
The ideal B12 supplement contains a mix of methylcobalamin, hydroxocobalamin and adenosylcobalamin (11)
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