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All four D50 codes are active for services October 1, 2025 through September 30, 2026 under the FY2026 ICD-10-CM April 1, 2026 release

Metabolic Health Benefits Beyond Weight Loss Weight loss represents the headline result, but both medications produce significant improvements in metabolic health markers that matter for long-term outcomes

Figure 2 Gut microbiota composition, diversity, and risk factors The bacterial composition, diversity, and abundance are highly influenced by genetic changes in the hosts genome, and by external variables such as the hosts lifestyle, diet, sanitation, health, and the use of antibiotics and probiotics (51)