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Collagen peptides are the one part of this shelf with real human trials and the effect size is modest, not transformative

Temperature sensitivity changes

Demonstrates marked gastroprotective and ulcer-healing activity in rodent models of IBD, NSAID damage, and fistula formation, mirroring the protective role of the parent protein in human gastric juice is exposed to daily

Whilst the quantities are minuscule and generally harmless, individuals with impaired kidney function may theoretically have reduced capacity to eliminate this cyanide with very high doses over extended periods, though this remains largely theoretical at normal supplemental doses