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These alternative weight-loss interventions may not be equally available or affordable to people with obesity in routine clinical practice, but might be adopted more by trial participants if they are made available as part of the trial

Probiotic supplementation is generally beneficial for GLP-1 users experiencing constipation, particularly strains like Bifidobacterium lactis BB-12 and Lactobacillus rhamnosus GG that have demonstrated improvements in transit time and stool consistency

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