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NICE has approved semaglutide 2.4 mg (Wegovy) for use within specialist weight management services (NICE TA875), subject to specific eligibility criteria including a BMI of 35 kg/m or above (or 32.5 kg/m or above in people from certain ethnic minority backgrounds at higher metabolic risk) alongside at least one weight-related comorbidity

Additionally, many plans impose quantity limits or require step therapy with older medications first, further extending timelines

Additionally, inconsistent drug levels may affect tolerability

This personalized approach ensures that interventions are both effective and appropriate for the patients specific needs