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[10] [11] However, it is important to recognise that clinical trials may not capture every possible side effect, particularly those that are rare or occur in specific subpopulations

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Most of the data they did find came from studies in animals, including rats, and not humans

The role of GLP-1/GIP receptors: tirzepatide imbalanced and biased activation Human atrial and ventricular cardiomyocytes express the GLP1R within each of all chambers, and the sinoatrial (SA) node shows the highest level of GLP1R expression [11, 12]