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Kanamori H, Takemura G, Goto K, Tsujimoto A, Mikami A, Ogino A, et al

Key features of the quantitation of semaglutide using the SCIEX 7500 system Low-ng/mL level quantitation of a high-potency GLP-1 analog: Achieve a 0.2 ng/mL LLOQ for semaglutide in rat plasma on the SCIEX 7500 system Ideal analytical performance: Achieve accurate quantitative performance with %CV 0.99

Tirzepatide, a dual GIP/GLP-1 receptor agonist, has demonstrated a greater reduction in HbA1c (up to 2.4%) than conventional GLP-1 agonists [4]

In 2009, the first unimolecular gut hormone receptor co-agonist, a glucagon/GLP-1 receptor co-agonist, was discovered and validated in preclinical models [76]