glp 1 physiology informs the pharmacotherapy of obesity Frontiers The Multifaceted Nature of GLP-1:

Inflammatory cytokines such as TNF-, IL-6, and IL-1 further potentiate DC activation and antigen presentation ( + T cell recognition ( The dysfunction of antigen presentation by DCs is closely related to the damage and apoptosis of melanocytes ( + T cells could therefore disrupt a key step in the autoimmune cascade

This one of the reasons why Ashwagandha is also referred to as winter cherry

Hansen HH, HM AE, Oro D, et al (2020) Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis

This is why sleep disorders like sleep apnea, fragmentation, and insomnia are more prevalent in older adults