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On the other hand, EBERs can also cause monocytes to become activated and differentiate into dendritic cells via activation of TLR3 receptors, which results in the release of high levels of IL-12 leading to activation of NK cells (CD16-CD56 bright ) [233]
Lyophilised AOD9604 is typically stored sealed, protected from light, and cold for long-term laboratory storage
First, optimal dosing in humans remains undefined, with current practice based primarily on extrapolation from animal studies and anecdotal clinical experience rather than formal dose-finding studies
Mullen et al, 2011)
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