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Retatrutide produced average weight loss of 19.7% in diabetic trial participants taking the 8mg dose
slowed gastric emptying (gastroparesis) GLP-1 agonists stimulate GLP-1 receptors in the CNS including vagal efferent fibers in the brainstem
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Neurons conduct a first relay in the solitary nucleus, located in the dorsolateral part of the bulb, and then make a second relay in the ventromedial nucleus of the thalamus before they project into the cortical or other area, involved in identifying taste (type and intensity)
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