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Peake, J.M., et al
That table contains the honest picture
Phase 2 clinical trial data published in the New England Journal of Medicine (Jastreboff et al., 2023) demonstrated mean body weight reductions of up to approximately 24% over 48 weeks in adults with obesity a notable finding, though long-term durability data and head-to-head comparisons with other treatments are not yet available
Clinicians will typically try standard prenatal vitamins or oral supplementation first, resorting to IM/IV B-complex therapy if those are inadequate or not feasible
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