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In the PIONEER 1 study (31), which investigated monotherapy with oral semaglutide in type 2 diabetes, participants on 14 mg semaglutide experienced an average weight loss of 4 kg after 26 weeks (31)
The notion that taking B12 before workouts will increase fat burning or improve performance is not supported by clinical data in individuals with adequate B12 status
But this has been steady since 2018
It is more closely associated with BDNF, neuroplasticity, and post-stroke cognitive support
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