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SpragueDawley rats (~ 250 g) were anesthetized by intraperitoneal injection of Beuthanasia-D (38 mg pentobarbital sodium and 6 mg phenytoin sodium/230 g rat) (Schering-Plough Animal Health Corp., Union, NJ)
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Epidermal Growth Factor 3500mg
[2] [23] The specific continuation criteria for treatment vary by product and are outlined in the respective NICE technology appraisals
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