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The catalytic cycle of Grx2 is also quite similar to Grx1 except that the Grx2SSG intermediate can be reduced by NADPH and TrxRD
Additionally, MCT2 is chiefly responsible for transporting lactate into metabolically active tissues with rich blood supply [46]
Vpr induces oxidative stress by stabilizing p53 protein, increasing transforming growth factor-beta protein levels and ROS production, and suppressing antioxidant enzymes 118,119,120
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