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It's found in relatively high concentrations in several bodily tissues and plays critical roles in mitigating oxidative stress and inflammation, maintaining redox balance, enhancing metabolic detoxification processes, and regulating immune function 2
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Given that there was no difference in total GSH between Preparation Condition 1 and Preparation Condition 2, and that free GSH is significantly higher in Preparation Condition 1 than in Preparation Condition 2, these results suggest that EDTA-treatment more effectively prevents spontaneous oxidation of free GSH in plasma than does heparinization of samples
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