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Scientific Classification A small-molecule quinolinium derivative and selective nicotinamide N-methyltransferase (NNMT) inhibitor

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The enzyme was dissolved in phosphate-buffered saline at pH 7.4, sterilized through a 0.22-m membrane, and administered under ultrasound guidance

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Complementary Approaches: The selectivity of AOD-9604 allows flexible combination with other interventions

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