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(Earlier research found that a higher 4.5-mg dose of cagrilintide led to 10% weight loss after 26 weeks in adults without diabetes.) But combining the two peptides and tackling appetite hormones from different but complementary angles appears to be more effective than either peptide alone

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Retatrutide is an unlicensed investigational peptide in the UK with no MHRA or EMA marketing authorisation as of 2024