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Aging, chronic stress, environmental exposure, poor sleep, and illness can all deplete levels over time, says Patel

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Dreiem A, Gertz C, Seegal R (2005) The effects of methylmercury on mitochondrial function and reactive oxygen species formation in rat striatal synaptosomes are age-dependent

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The risk, however, lies less with the molecule itself than with the quality of the preparation and the conditions of administration: a cluster of seven cases of endotoxin poisoning was described after infusions prepared from contaminated raw material not intended for intravenous use (Johnstone et al., Epidemiology and Infection 2018, PMID 29673413)

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Blots were incubated overnight at 4 C with primary antibodies and 2 h with HRP-conjugated secondary antibodies at room temperature

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