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The half-life of a drug is the time it takes for half of the drug to be eliminated from the body
Tirzepatide dosing should follow FDA-approved protocols: initiate at 2.5 mg subcutaneously once weekly for four weeks, then increase to 5 mg weekly
The bidirectional effects of NMDA receptor antagonism on feeding could potentially diminish the weight-lowering efficacy of systemic exposure to NMDA receptor antagonists
Missing doses or inconsistent administration can lead to suboptimal therapeutic outcomes and potentially increased side effects when restarting
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