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Endogenous hyperinsulinemia may cause weight gain and obesity [30], and treatment with insulin causes substantial weight gain, and may even increase cardiovascular risk [31]
Storage: e.g., 20 C (protect from light) Stability: Lyophilized form remains stable when stored under recommended conditions
The evidence base for tirzepatide as monotherapy is robust, with pivotal trials including SURMOUNT-1 demonstrating significant weight reduction in adults with obesity, and SURPASS trials establishing glycemic efficacy in type 2 diabetes
These therapies bypass digestion to maximise absorption and effectiveness
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