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4.3 Pharmacokinetic parameters in Sprague-Dawley rats after intravenous and intramuscular administration A total of 324 SD rats were randomly divided into five groups, including 66 rats in group one, 60 rats each in groups two to four, and 78 rats in group five, with each group comprising half male and half female subjects
Future multi-region MRS studies examining GSH simultaneously in the thalamus, occipital cortex, and other brain regions within the same patients would help clarify whether GSH reduction is specific to the thalamus or represents a more widespread phenomenon
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