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As Imperial College Londons Ivan Koychev noted: People exposed to GLP-1RAs over many years appear to have a lower risk of ever developing dementia, which suggests an influence on the earliest pathogenic processes rather than on established neurodegeneration. 2
However, it requires careful handling
These include GLP1 plus agents, which combine the known advantages of GLP1RAs with the activity of additional hormones, such as glucose-dependent insulinotropic peptide, glucagon and amylin, to achieve desired therapeutic goals
Hence, T2D plays a vital role in CD development (Fig
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